Soluble urokinase plasminogen activator receptor (suPAR) in the emergency department: An update.

ABSTRACT:

Background

The biomarker soluble urokinase plasminogen activator receptor (suPAR) is an indicator of inflammation which is increased in a variety of chronic and acute disease states. Its most promising application in the emergency setting is to aid in the prognostic stratification of patients by identifying those at high risk of deterioration. This is a narrative review of studies evaluating the use of suPAR.

Methods

We conducted a Medline search for studies on the use of suPAR in patients acutely admitted to the emergency department.

Results

25 original studies were included in the review. suPAR as a marker of inflammation has been used alone or combined to other inflammatory biomarkers in the assessment of patients suffering from various acute and chronic diseases i

SUBMITTER: Velissaris D 

PROVIDER: S-EPMC9659827 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature