Association between poor sleep quality and an increased risk of dry eye disease in patients with obstructive sleep apnea syndrome.

ABSTRACT:

Purpose

Obstructive sleep apnea (OSA) is related to an increased incidence of dry eye disease (DED). However, their exact relationship is unknown and requires further well-designed studies with advanced mechanisms detection.

Patients and methods

This case-control study included 125 OSA cases and 125 age-gender-matched controls enrolled in the hospital between 1 January and 1 October 2021. OSA diagnosis and classification were performed using a polysomnography (PSG) assay. Detailed ophthalmological examinations, including the Schirmer I test, corneal staining, and ocular surface disease index (OSDI), were used to detect DED-related parameters. A comprehensive ocular surface assay was performed to measure a series of parameters, including first non-invasive first tear film bre

SUBMITTER: Pu Q 

PROVIDER: S-EPMC9659957 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature