Early life environmental antibiotic exposure and preschool allergic diseases: A biomonitoring-based prospective study in eastern China.

ABSTRACT:

Background

Globally, the prevalence of allergic diseases remains high, as does the level of environmental antibiotics. It has been found that clinical antibiotic application may increase preschool allergy risk. However, few biomonitoring studies have been conducted about the association between early life environmental trace dose antibiotic exposure and preschool allergy.

Objective

To analyze the association between prenatal environmental antibiotic levels and allergic diseases using logistic regression models.

Methods

A total of 743 pregnant women and their offspring from the Shanghai Allergy Birth Cohort completed five years follow-up, and 251 mother-infant pairs were finally included. Maternal urine samples were collected for 15 antibiotic quantitative measurements

SUBMITTER: Zheng H 

PROVIDER: S-EPMC9659984 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature