Inflammatory bowel disease-associated malignancies and considerations for radiation impacting bowel: a scoping review.

ABSTRACT:

Background

Inflammatory bowel disease (IBD), subdivided into Crohn's disease (CD) and ulcerative colitis (UC), is an auto-inflammatory gastrointestinal condition with an established increased risk of certain malignancies. Compared to sporadic cancers in the general population, IBD-associated malignancies present unique challenges to providing quality care. Radiation therapy (RT) targeting IBD-associated malignancies may directly impact inflamed bowel, with special considerations for the risk of toxicities. Historically, patients with IBD have been less likely to receive radiotherapy in proximity to bowel due to a poor understanding of the potential for acute and chronic toxicities and unclear treatment outcomes. We present a scoping review, to more fully assess IBD-associated malig

SUBMITTER: Bodofsky S 

PROVIDER: S-EPMC9660071 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature