An Item-Response Mapping from General Health Questionnaire Responses to EQ-5D-3L Using a General Population Sample from England.

ABSTRACT:

Background

The 12-item General Health Questionnaire (GHQ-12) is widely used to measure mental health and well-being; however, it is not possible to estimate values on the full health = 1, dead = 0 scale used to construct quality-adjusted life-years (QALYs) from GHQ-12 responses as it is not preference-based.

Objective

The aim of this study was to create an item-response mapping between GHQ-12 and EQ-5D-3L health states, for which several value sets exist.

Methods

Data from the 2012 Health Survey for England with complete GHQ-12 and EQ-5D-3L descriptive system responses were used for analysis. Data were split 70/30 into estimation/test samples. Four modelling approaches, with EQ-5D-3L levels on each dimension as dependent variables and GHQ-12 responses as independent v

SUBMITTER: Webb EJD 

PROVIDER: S-EPMC9660137 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature