Incidence of stroke, systemic embolism and bleeding events in patients without anticoagulation based on real-world data in Japan: a retrospective cohort study.

ABSTRACT:

Objectives

To examine the incidence of stroke or systemic embolic events (SSEs) and bleeding events in untreated patients with non-valvular atrial fibrillation (NVAF) after widespread use of direct oral anticoagulant agents (DOACs).

Design

Multicentre, non-interventional, observational, retrospective cohort study using real-world data in Japan (2016-2018).

Setting

The Mie, Musashino University study of NVAF, which used the Mie-Life Innovation Promotion Center Database. This is a regional clinical database involving one university hospital and eight general hospitals in Mie Prefecture in Japan.

Participants

Japanese patients with NVAF (n=7001).

Primary and secondary outcome

The incidence of SSEs and bleeding events.

Results

A total of 7001 patients

SUBMITTER: Tanizawa K 

PROVIDER: S-EPMC9660567 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature