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Longitudinal developmental trajectories of inhibition and white-matter maturation of the fronto-basal-ganglia circuits.


ABSTRACT: Response inhibition refers to the cancelling of planned (or restraining of ongoing) actions and is required in much of our everyday life. Response inhibition appears to improve dramatically in early development and plateau in adolescence. The fronto-basal-ganglia network has long been shown to predict individual differences in the ability to enact response inhibition. In the current study, we examined whether developmental trajectories of fiber-specific white matter properties of the fronto-basal-ganglia network was predictive of parallel developmental trajectories of response inhibition. 138 children aged 9-14 completed the stop-signal task (SST). A subsample of 73 children underwent high-angular resolution diffusion MRI data for up to three time points. Performance on the SST was assesse

SUBMITTER: Singh M 

PROVIDER: S-EPMC9660590 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature