Induction of labour for predicted macrosomia: study protocol for the 'Big Baby' randomised controlled trial.

ABSTRACT:

Introduction

Large-for-gestational age (LGA) fetuses have an increased risk of shoulder dystocia. This can lead to adverse neonatal outcomes and death. Early induction of labour in women with a fetus suspected to be macrosomic may mitigate the risk of shoulder dystocia. The Big Baby Trial aims to find if induction of labour at 38⁺⁰-38⁺⁴ weeks' gestation, in pregnancies with suspected LGA fetuses, reduces the incidence of shoulder dystocia.

Methods and analysis

The Big Baby Trial is a multicentre, prospective, individually randomised controlled trial of induction of labour at 38⁺⁰ to 38⁺⁴ weeks' gestation vs standard care as per each hospital trust (median gestation of delivery 39⁺⁴) among women whose fetuses have an esti

SUBMITTER: Ewington LJ 

PROVIDER: S-EPMC9660609 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature