The Role of Microelectrode Recording in Deep Brain Stimulation Surgery for Parkinson's Disease: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

STN-DBS is a cornerstone in the treatment of advanced Parkinson's disease (PD). The traditional approach is to use an awake operative technique with microelectrode recording (MER). However, more centers start using an asleep MRI-guided technique without MER.

Objective

We systematically reviewed the literature to compare STN-DBS surgery with and without MER for differences in clinical outcome.

Methods

We systematically searched PubMed, Embase, MEDLINE, and Web of Science databases for randomized clinical trials and consecutive cohort studies published between 01-01-2000 and 26-08-2021, that included at least 10 PD patients who had received bilateral STN-DBS.

Results

2,129 articles were identified. After abstract screening and full-text review, 26 stud

SUBMITTER: Vinke RS 

PROVIDER: S-EPMC9661327 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature