Longitudinal and prospective assessment of prenatal maternal sleep quality and associations with newborn hippocampal and amygdala volume.

ABSTRACT:

Background

The rapid maturation of the fetal brain renders the fetus susceptible to prenatal environmental signals. Prenatal maternal sleep quality is known to have important health implications for newborns including risk for preterm birth, however, the effect on the fetal brain is poorly understood.

Method

Participants included 94 pregnant participants and their newborns (53% female). Pregnant participants (M_age = 30; SD_age= 5.29) reported on sleep quality three times throughout pregnancy. Newborn hippocampal and amygdala volumes were assessed using structural magnetic resonance imaging. Multilevel modeling was used to test the associations between trajectories of prenatal maternal sleep quality and newborn hippocampal and amygdala volume.

Results<

SUBMITTER: Nevarez-Brewster M 

PROVIDER: S-EPMC9661438 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature