The utility of the CADISS® system in the dissection of epidural fibrosis in revision lumbar spine surgery (A case series).

ABSTRACT: Spine surgery and spinal fusion surgery are rising. Revision rates following initial surgery are between 8 and 45%. Epidural fibrosis is a common response to spine surgery for most patients and increases complications in revision surgery. Previous research suggests using MESNA (Sodium 2-mercaptoethane sulfonate) in combination with mechanical blunt dissection safely reduces surgical complications. MESNA is a mucolytic agent which selectively cleaves disulphide bonds involved in the adherence and strength of fibrosis, meaning cutting instruments are not needed. The Chemically Assisted DISSection (CADISS®) System is an optimised non-cutting surgical device, consisting of a reconstitution cartridge for MESNA preparation, irrigated surgical instruments, and a footswitch to control MESNA releas

SUBMITTER: Makhchoune M 

PROVIDER: S-EPMC9661665 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature