Low lipoprotein(a) concentration is associated with atrial fibrillation: a large retrospective cohort study.

ABSTRACT:

Background and aims

The role of serum lipoprotein(a) [Lp(a)] levels in atrial fibrillation (AF) is still uncertain, especially in the Chinese population. Here, we aimed to elucidate the potential relationship between Lp(a) quantiles and AF.

Methods

All data were collected through inpatients with electronic health records from the Second Affiliated Hospital of Nanchang University, Jiangxi Province, China. The propensity score matching (PSM) method was used to match control and case groups. Interactions between AF, Lp(a) quantiles, and other clinical indices were analyzed by logistic regression and stratified analysis. Statistical analyses were performed with IBM SPSS statistical software and R software.

Results

From 2017 to 2021, 4,511 patients with AF and 9,022 patien

SUBMITTER: Tao J 

PROVIDER: S-EPMC9661736 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature