Prognostic and clinicopathological value of Slug protein expression in breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Many studies have reported the relationship between prognosis and Slug protein expression in breast cancer patients, but the results are discrepant. Therefore, there is a need for meta-analyses with high statistical power to investigate and further explore their relationship.

Methods

We used PubMed, Embase, the Cochrane Library, Scopus, MEDLINE, and the Web of Science to find studies on breast cancer and Slug. Overall survival (OS) and disease-free survival (DFS) were the study's primary endpoints. We pooled hazard ratios (HRs) and odds ratios (ORs) to assess the association between Slug protein expression and prognostic and clinicopathological parameters. This study was performed using STATA version 14.0 for data analysis. (Stata Corporation, TX, USA).

Results

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC9661812 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature