Adiposity and NMR-measured lipid and metabolic biomarkers among 30,000 Mexican adults.

ABSTRACT:

Background

Adiposity is a major cause of morbidity and mortality in part due to effects on blood lipids. Nuclear magnetic resonance (NMR) spectroscopy provides direct information on >130 biomarkers mostly related to blood lipid particles.

Methods

Among 28,934 Mexican adults without chronic disease and not taking lipid-lowering therapy, we examine the cross-sectional relevance of body-mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), and hip circumference (HC) to NMR-measured metabolic biomarkers. Confounder-adjusted associations between each adiposity measure and NMR biomarkers are estimated before and after mutual adjustment for other adiposity measures.

Results

Markers of general (ie, BMI), abdominal (ie, WC and WHR) and gluteo-femoral (ie, HC) adip

SUBMITTER: Aguilar-Ramirez D 

PROVIDER: S-EPMC9663185 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature