Association of sex steroid hormones and new bone formation rate after iliac onlay grafting: a prospective clinical pilot study.

ABSTRACT:

Purpose

The present prospective study evaluates the association between new bone formation rate in the iliac onlay graft and sex steroid hormone serum levels.

Methods

A total of 15 partially or completely edentulous postmenopausal females and 9 males with less than 5 mm height of the remaining alveolar bone underwent iliac onlay grafting followed by dental implant placement using a two-stage approach. Sex hormone binding globulin and 17β-estradiol serum levels were investigated by electrochemiluminescence immunoassay, while total testosterone level was analyzed using radioimmunoassay. At the time of implant placement, 12 weeks after grafting, bone biopsies were obtained and analyzed histomorphometrically. Statistical analysis was performed using linear mixed models.

Resul

SUBMITTER: Landwehr VC 

PROVIDER: S-EPMC9663769 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature