Tissue specific considerations in implementing high intensity focussed ultrasound under magnetic resonance imaging guidance.

ABSTRACT: High-intensity focused ultrasound can ablate a target permanently, leaving tissues through which it passes thermally unaffected. When delivered under magnetic resonance (MR) imaging guidance, the change in tissue relaxivity on heating is used to monitor the temperatures achieved. Different tissue types in the pre-focal beam path result in energy loss defined by their individual attenuation coefficients. Furthermore, at interfaces with different acoustic impedances the beam will be both reflected and refracted, changing the position of the focus. For complex interfaces this effect is exacerbated. Moreover, blood vessels proximal to the focal region can dissipate heat, altering the expected region of damage. In the target volume, the temperature distribution depends on the thermal conductivi

SUBMITTER: deSouza NM 

PROVIDER: S-EPMC9663991 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature