Influence of vitamin D supplementation on immune function of healthy aging people: A pilot randomized controlled trial.

ABSTRACT:

Objectives

This study aims to investigate the influence of vitamin D supplementation on immune function of healthy older adults.

Materials and methods

Designed as a randomized controlled trial, 21 participants (55-85 years) completed the study during May-November 2018 in Coventry, England. The participants were randomized into vitamin D or the control group, stratified by age, gender and body mass index. The vitamin D group (n = 12) took vitamin D3 tablets of 1,000 IU/day for 12 weeks plus vitamin D education leaflet, while the control group (n = 9) were only provided with the leaflet. At baseline, 6 and 12 weeks, plasma 25(OH)D levels and immunological and metabolic parameters including phagocytic activity of granulocytes and monocytes, tumor necrosis factor,

SUBMITTER: Dong H 

PROVIDER: S-EPMC9664161 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature