Vascular Reactivity Index and PELOD-2 as a mortality predictor in paediatric septic shock: a single-centre retrospective study

ABSTRACT:

Background

The mortality rate for children with septic shock is stil quite high in low-income and middle-income countries (31.7%). One of the most widely used scoring systems to assess mortality in sepsis or septic shock is Paediatric Logistic Organ Dysfunction 2 (PELOD-2). However, it requires various laboratory evaluations. A non-invasive, fast and easy method is needed to assess the mortality of children with septic shock at an early stage. Therefore, this study aims to evaluate the ability of Vascular Reactivity Index (VRI) compared with PELOD-2 score as a predictor of mortality in children with septic shock based on vascular response to vasoactive agents.

Methods

A retrospective cohort study was conducted using data from children aged 1 month to 18 years with septic

SUBMITTER: Yuniar I 

PROVIDER: S-EPMC9664308 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature