Selective sensing of adenosine monophosphate (AMP) by a calix[6]triazolium-based colorimetric sensing ensemble.

ABSTRACT: Since adenosine monophosphate (AMP) is closely related to many diseases, the measurement of AMP is important for the diagnosis and treatment of related diseases. Among the AMP sensors reported thus far, sensors that selectively recognize AMP, not ADP or ATP, are rare, and complex experimental procedures and additional instruments are required for AMP recognition. We developed a colorimetric chemosensor using calix[6]triazolium (CT6) and intended to use it for the simple and rapid detection of AMP. Colorimetric AMP detection was established through an indicator displacement assay (IDA) in which CT6 and Brooker's merocyanine (BM) were used as receptors and indicators, respectively. The change in the absorption spectrum and color of BM showed that the binding affinity of CT6 to AMP conferred

SUBMITTER: Cho J 

PROVIDER: S-EPMC9664555 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature