Visit-to-visit variability in blood pressure and kidney disease progression in IgA nephropathy.

ABSTRACT:

Background

The visit-to-visit variability (VVV) in blood pressure (BP) is an important risk factor for stroke and coronary heart disease and may also be associated with kidney damage and the development of chronic kidney disease (CKD). Data on the association between VVV in BP and the risk of CKD progression among patients with immunoglobulin A nephropathy (IgAN) are limited. We aimed to evaluate the relationships of VVV in BP with the progression of IgAN.

Methods

We assessed 1376 patients with IgAN at Peking University First Hospital. The main VVV in BP was expressed as the standard deviation (SD), coefficient of variation (CV) and average real variability (ARV). The associations of variability in BP with composite kidney disease progression events, defined as a 50% decline

SUBMITTER: Tang C 

PROVIDER: S-EPMC9664579 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature