Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer's disease.

ABSTRACT:

Background

The enrollment into clinical trials of persons at risk for autosomal dominant Alzheimer's disease (ADAD) in whom the onset of disease can be accurately predicted facilitates the interpretation of outcomes (e.g., biomarkers, treatment efficacy). Attitudes toward involvement in such studies are biased by intrinsic cultural and social characteristics. Our objective was to study how demographic factors such as country of residence, age, sex, schooling, parenthood, and urbanization affect attitudes towards participation in hypothetical clinical trials in Mexican families at risk for ADAD living either in Mexico or in the United States.

Methods

Participants were 74 members of different families known to harbor an ADAD mutation living in Mexico (n = 50) or in the United

SUBMITTER: Zuno-Reyes A 

PROVIDER: S-EPMC9664662 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature