Effects of General Anesthesia on Changes of Serum Hepatitis B Virus-DNA Levels in Infected Patients Underwent Non-Hepatobiliary Minimally Invasive Surgery: A Pilot Observational Study.

ABSTRACT:

Objective

To investigate the effects of different general anesthesia methods on the changes of serum hepatitis B virus deoxyribonucleic acid (HBV-DNA) levels in the hepatitis B virus (HBV) infected patients.

Methods

This pilot prospective observational study was carried out from March 2021 to January 2022. Forty patients infected by HBV, who underwent non-hepatobiliary minimally invasive surgery, were allocated into an intravenous anesthesia group maintained with propofol (Group P, n = 20) and an inhalation anesthesia group maintained with sevoflurane (Group S, n = 20) by a random envelope method. Patient's blood was drawn before operation (T_baseline), at 24 hours (T_{post 24hrs}) and 48 hours (T_{post 48hrs}) after operation to detect the serum HB

SUBMITTER: Quan J 

PROVIDER: S-EPMC9664914 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature