In silico identification and in vitro expression analysis of breast cancer-related m⁶A-SNPs.

ABSTRACT: Research on m⁶A-associated SNPs (m⁶A-SNPs) has emerged recently due to their possible critical roles in many key biological processes. In this sense, several investigations have identified m⁶A-SNPs in different diseases. In order to gain a more complete understanding of the role that m⁶A-SNPs can play in breast cancer, we performed an in silico analysis to identify the m⁶A-SNPs associated with breast cancer and to evaluate their possible effects. For this purpose, we downloaded SNPs related to breast cancer and a list of m⁶A-SNPs from public databases in order to identify which ones appear in both. Subsequently, we assessed the identified m⁶A-SNPs in silico by expression quantitative trait loci (eQTL

SUBMITTER: Kleinbielen T 

PROVIDER: S-EPMC9665143 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature