Molecular diversity of hepatitis B virus among pregnant women in Amhara National Regional State, Ethiopia.

ABSTRACT:

Background

Despite the availability of effective vaccines and treatments for hepatitis B virus (HBV), it continues to be a major public health problem in sub-Saharan Africa including Ethiopia. Routine screening for HBV in pregnant women is widely recommended, but there is lack of screening for HBV during pregnancy in Ethiopia. Therefore, this study aimed to assess viral load, and genetic diversity among pregnant women in the Amhara National Regional State, Ethiopia.

Materials and methods

Hepatitis B surface antigen (HBsAg) testing was performed on 1846 pregnant women, 85 of who tested positive were included in this study. HBV DNA was isolated from 85 positive sera, and the partial surface/polymerase gene was amplified and sequenced. HBV genotypes, sub-genotypes, serotypes an

SUBMITTER: Dagnew M 

PROVIDER: S-EPMC9665361 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature