CITEdb: a manually curated database of cell-cell interactions in human.

ABSTRACT:

Motivation

The interactions among various types of cells play critical roles in cell functions and the maintenance of the entire organism. While cell-cell interactions are traditionally revealed from experimental studies, recent developments in single-cell technologies combined with data mining methods have enabled computational prediction of cell-cell interactions, which have broadened our understanding of how cells work together, and have important implications in therapeutic interventions targeting cell-cell interactions for cancers and other diseases. Despite the importance, to our knowledge, there is no database for systematic documentation of high-quality cell-cell interactions at the cell type level, which hinders the development of computational approaches to identify cell-

SUBMITTER: Shan N 

PROVIDER: S-EPMC9665858 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature