Strategy for Calculating Magnesium Sulfate Dose in Obese Patients: A Randomized Blinded Trial.

ABSTRACT:

Background

Magnesium sulfate has analgesic properties during the postoperative period. However, there is a knowledge gap in pharmacology related to the use of the real, ideal, or corrected ideal body weight to calculate its dose in obese patients. This trial compared postoperative analgesia using actual and corrected ideal body weight.

Methods

Seventy-five obese patients scheduled to undergo laparoscopic gastroplasty or cholecystectomy under general anesthesia were randomly assigned to three groups. The patients in the control group did not receive magnesium sulfate; the other two groups received magnesium sulfate at 40 mg·kg^-1 of actual body weight or corrected ideal body weight.

Results

In patients with body mass index >30 mg·kg^-2 (mean body ma

SUBMITTER: Silva Filho SE 

PROVIDER: S-EPMC9666020 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature