The effect of AT1R-1166A/C and AT2R-1675A/G polymorphisms on susceptibility to preeclampsia: A systematic review and meta-analysis.

ABSTRACT:

Background

The aim of this meta-analysis is to investigate the association between Angiotensin II type 1 receptor (AT1R)-1166A/C, Angiotensin II type 2 receptor (AT2R)-1675A/G polymorphisms and susceptibility to preeclampsia (PE).

Methods

Online databases, including Web of Science, PubMed, EMBASE, CINAHL, CENTRAL, Scopus, Lilacs/SciELO, and Chinese National Knowledge Infrastructure, China Wan Fang, China Science and Technology Journal Database, were used to perform the literature search up to April 2022. The odds ratio (OR) and 95% confidence interval (CI) were used as effect size. The data was analyzed by Stata 15.0 software.

Results

According to the inclusion and exclusion criteria, a total of 22 case-control studies were identified, including 3524 cases and 6308 co

SUBMITTER: Quan Y 

PROVIDER: S-EPMC9666145 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature