The intrafollicular concentration of leptin as a potential biomarker to predict oocyte maturity in in-vitro fertilization.

ABSTRACT: Oocyte maturity is critical to the development potential of the embryo and pregnancy outcomes in natural and in-vitro fertilization (IVF). In IVF, oocyte maturity is typically evaluated using morphological criteria, although such assessment remains highly subjective. To identify reliable biomarkers of oocyte maturity, this study investigates the relationship between follicular cytokine concentrations and oocyte maturity in IVF patients with different ovarian reserves. In this prospective study, follicular fluid was collected during oocyte retrieval and the concentrations of cytokines involved in ovarian folliculogenesis were determined. Follicular fluid cytokine concentrations were compared between participants in three groups according to serum anti-Mullerian hormone (AMH) concentration,

SUBMITTER: Hong KJ 

PROVIDER: S-EPMC9666526 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature