The role of involved field irradiation versus elective nodal irradiation in definitive radiotherapy or chemoradiotherapy for esophageal cancer- a systematic review and meta-analysis.

ABSTRACT:

Objective

This study aimed to analyze whether involved field irradiation (IFI) is associated with improving survival outcomes and reducing adverse events compared with elective nodal irradiation (ENI) in patients of esophageal cancer who underwent definitive radiotherapy or chemoradiotherapy.

Summary background data

Radiotherapy plays an important role for not surgery patients. However, the role of radiation target size is still uncertain.

Methods

We searched Web of Science, Embase, PubMed, and Cochrane Central for English and non-English publications comparing esophageal cancer patients who received radiotherapy with IFI with those with ENI. Primary outcomes included overall survival (OS) and adverse events related to radiotherapy. The risk of bias was assessed using

SUBMITTER: Wang H 

PROVIDER: S-EPMC9666894 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature