Assessing the feasibility of sustaining SARS-CoV-2 local containment in China in the era of highly transmissible variants.

ABSTRACT:

Background

The SARS-CoV-2 containment strategy has been successful in mainland China prior to the emergence of Omicron. However, in the era of highly transmissible variants, whether it is possible for China to sustain a local containment policy and under what conditions China could transition away from it are of paramount importance at the current stage of the pandemic.

Methods

We developed a spatially structured, fully stochastic, individual-based SARS-CoV-2 transmission model to evaluate the feasibility of sustaining SARS-CoV-2 local containment in mainland China considering the Omicron variants, China's current immunization level, and nonpharmaceutical interventions (NPIs). We also built a statistical model to estimate the overall disease burden under various hypothetical

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9666984 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature