Targeting highly resisted anticancer drugs through topological descriptors using VIKOR multi-criteria decision analysis.

ABSTRACT: The disease cancer is expanding on high spans in virtually all over the world, and undoubtedly, the research through all the aspects of sciences for each of its perspective is a great cause in reducing its severeness and symptoms. Chemotherapy is itself a cure to cancer as it helps in controlling the formation of cancerous cells but leaving multiple side effects on a human body. In this research work, we targeted 21 anticancer drugs that are in taken by the patients in combinations during chemotherapies. We introduce another branch of mathematics named as OR (Operations Research) linking to the chemical graph theory. Chemical graph theory allows us to generate highly resistant research on any structure via quantitative structure property relationship (QSPR) modeling to explore and develop

SUBMITTER: Li Y 

PROVIDER: S-EPMC9667010 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature