Association between glucosamine use and cancer mortality: A large prospective cohort study.

ABSTRACT:

Objective

Previous studies have shown anti-cancer and anti-inflammatory benefits of glucosamine. This study was performed to prospectively evaluate the association between glucosamine supplementation and the mortality of multiple cancers based on the UK Biobank cohort study.

Materials and methods

A total of 453,645 participants aged 38-73 who had no cancer at baseline were recruited between 2006 and 2010 and followed until March 2021. We used cox and poission proportional hazards models to explore the association between habitual use of glucosamine and cancer mortality. Subgroup analyses were conducted to understand the potential effect modifications of demographics, lifestyle factors, and health outcomes. Sensitivity analyses were performed to determine the robustness of th

SUBMITTER: Zhou J 

PROVIDER: S-EPMC9667031 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature