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Development and implementation of a clinical decision support system tool for the evaluation of suspected monkeypox infection.


ABSTRACT: Monkeypox virus was historically rare outside of West and Central Africa until the current 2022 global outbreak, which has required clinicians to be alert to identify individuals with possible monkeypox, institute isolation, and take appropriate next steps in evaluation and management. Clinical decision support systems (CDSS), which have been shown to improve adherence to clinical guidelines, can support frontline clinicians in applying the most current evaluation and management guidance in the setting of an emerging infectious disease outbreak when those guidelines are evolving over time. Here, we describe the rapid development and implementation of a CDSS tool embedded in the electronic health record to guide frontline clinicians in the diagnostic evaluation of monkeypox infection and triage patients with potential monkeypox infection to individualized infectious disease physician review. We also present data on the initial performance of this tool in a large integrated healthcare system.

SUBMITTER: Albin JS 

PROVIDER: S-EPMC9667162 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Development and implementation of a clinical decision support system tool for the evaluation of suspected monkeypox infection.

Albin John S JS   Lazarus Jacob E JE   Hysell Kristen M KM   Rubins David M DM   Germaine Lindsay L   Dugdale Caitlin M CM   Heller Howard M HM   Hohmann Elizabeth L EL   Baugh Joshua J JJ   Shenoy Erica S ES  

Journal of the American Medical Informatics Association : JAMIA 20221101 12


Monkeypox virus was historically rare outside of West and Central Africa until the current 2022 global outbreak, which has required clinicians to be alert to identify individuals with possible monkeypox, institute isolation, and take appropriate next steps in evaluation and management. Clinical decision support systems (CDSS), which have been shown to improve adherence to clinical guidelines, can support frontline clinicians in applying the most current evaluation and management guidance in the  ...[more]

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