Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals.

ABSTRACT:

Importance

Ascending thoracic aortic disease is an important cause of sudden death in the US, yet most aortic aneurysms are identified incidentally.

Objective

To develop and validate a clinical score to estimate ascending aortic diameter.

Design, setting, and participants

Using an ongoing magnetic resonance imaging substudy of the UK Biobank cohort study, which had enrolled participants from 2006 through 2010, score derivation was performed in 30 018 participants and internal validation in an additional 6681. External validation was performed in 1367 participants from the Framingham Heart Study (FHS) offspring cohort who had undergone computed tomography from 2002 through 2005, and in 50 768 individuals who had undergone transthoracic echocardiography in the Community

SUBMITTER: Pirruccello JP 

PROVIDER: S-EPMC9667326 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature