Intrinsic Fluorescence in Peptide Amphiphile Micelles with Protein-Inspired Phosphate Sensing.

ABSTRACT: Although peptide amphiphile micelles (PAMs) have been widely studied since they were developed in the late 1990s, to the author's knowledge, there have been no reports that PAMs intrinsically fluoresce without a fluorescent tag, according to the aggregation-induced emission (AIE) effect. This unexpected fluorescence behavior adds noteworthy value to both the peptide amphiphile and AIE communities. For PAMs, intrinsic fluorescence becomes another highly useful feature to add to this well-studied material platform that features precise synthetic control, tunable self-assembly, and straightforward functionalization, with clear potential applications in bioinspired materials for bioimaging and fluorescent sensing. For AIE, it is extremely rare and highly desirable for one platform to exhibit p

SUBMITTER: Fowler WC 

PROVIDER: S-EPMC9667461 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature