Impact of time between thrombolysis and endovascular thrombectomy on outcomes in patients with acute ischaemic stroke.

ABSTRACT:

Background

Benefits of endovascular thrombectomy (ET) after intravenous thrombolysis (IVT) for patients with acute ischaemic stroke (AIS) have been demonstrated, but analyses of the relationship between IVT-ET time delay and functional outcomes among patients receiving both treatments are lacking.

Methods

We used data from the "Berlin-Specific Acute Treatment in Ischaemic and haemorrhAgic stroke with Long-term outcome" (B-SPATIAL) registry. Between January 1st, 2016 and December 31st, 2019, we included patients who received both IVT and ET. The primary outcome was the 3-month ordinal modified Rankin scale (mRS) score. The IVT-ET time delay was analyzed in categories and continuously. We used adjusted ordinal logistic regression to estimate common odds ratios (cOR) and 95% co

SUBMITTER: Wagner L 

PROVIDER: S-EPMC9667508 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature