Application of protective weight-bearing in osteonecrosis of the femoral head: A systematic review and meta-analysis of randomized controlled trials and observational studies.

ABSTRACT:

Background

The aim of this systematic review and meta-analysis was to estimate the efficacy and prognostic value of protective weight-bearing for ONFH.

Methods

The authors searched the PubMed, EMBASE and Cochrane Library databases, up to February 25, 2022. RCTs and observational studies on conservative treatment, including the use of crutches, for skeletally mature patients with ONFH and written in English were included. Outcomes were the total hip arthroplasty (THA) rate, collapse rate, Hip Harris score (HHS) and visual analog scale (VAS) score. Cochrane Review Manager Software 5.4 and Stata 15.1 were used to perform the statistical analyses.

Results

A total of 14 studies involving 813 patients (1,025 hips) were included in this meta-analysis. The results showed that

SUBMITTER: Chen WH 

PROVIDER: S-EPMC9667948 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature