Development and validation of a prognostic nomogram for extrahepatic bile duct adenocarcinoma.

ABSTRACT:

Objective

The aim of this study is to establish a prognostic nomogram for patients with extrahepatic bile duct adenocarcinoma (EBDA).

Methods

From the Surveillance, Epidemiology, and End Results database, we retrieved clinical data from 1,485 patients diagnosed with EBDA between 2004 and 2015. These patients were randomly assigned to either the training or validation group in a ratio of 2:1. Cox proportional risk regression models were used to analyze the association of each variable with overall survival (OS). Univariate and multifactorial Cox regression analyses were performed to identify prognostic factors, and prognostic nomograms were created on the basis of the results of Cox multifactorial regression analysis. Performance was assessed by calibration curves and ROC cur

SUBMITTER: Zhang S 

PROVIDER: S-EPMC9668252 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature