Adolescents with a concussion have altered brain network functional connectivity one month following injury when compared to adolescents with orthopedic injuries.

ABSTRACT: Concussion is a mild traumatic brain injury (mTBI) with increasing prevalence among children and adolescents. Functional connectivity (FC) within and between the default mode network (DMN), central executive network (CEN) and salience network (SN) has been shown to be altered post-concussion. Few studies have investigated connectivity within and between these 3 networks following a pediatric concussion. The present study explored whether within and between-network FC differs between a pediatric concussion and orthopedic injury (OI) group aged 10-18. Participants underwent a resting-state functional magnetic resonance imaging (rs-fMRI) scan at 4 weeks post-injury. One-way ANCOVA analyses were conducted between groups with the seed-based FC of the 3 networks. A total of 55 concussion and 27

SUBMITTER: Healey K 

PROVIDER: S-EPMC9668608 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature