Alterations in metamemory capacity and neural correlates in a subtype of subjective cognitive decline.

ABSTRACT:

Backgrounds

Subjective cognitive decline (SCD), one of the important clinical indicators for preclinical Alzheimer's disease (AD), is primarily defined as self-perceived cognitive decline without objective evidence for cognitive impairment. However, the accuracy of their self-evaluation of cognition is unclear. This study sought to investigate the capacity for self-evaluation of own cognitive performance in SCD by applying an objective metamemory paradigm.

Methods

147 individuals with SCD were classified into four subgroups by their subjective feeling of worse performance than peers or not (P+/-) and whether they have objectively slight cognitive impairment compared to normative data (S+/-). Metamemory scores, the amplitude of the low-frequency fluctuation (ALFF), fractional

SUBMITTER: Li Q 

PROVIDER: S-EPMC9668650 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature