Inter-hemispheric synchronicity and symmetry: The functional connectivity consequences of stroke and neurodegenerative disease.

ABSTRACT: Stroke and neurodegenerative diseases differ along several dimensions, including their temporal trajectories -abrupt onset versus slow disease progression. Despite these differences, they can give rise to very similar cognitive impairments, such as specific forms of aphasia. What has been scarcely investigated, however, is the extent to which the underlying functional neuroplastic consequences are similar or different for these diseases. Here, for the first time, we directly compare changes in the brain's functional network connectivity, measured with resting-state fMRI, in stroke and progressive neurological disease. Specifically, we examined two groups of individuals with chronic post-stroke aphasia or non-fluent primary progressive aphasia, matched for their behavioral profiles and dist

SUBMITTER: Tao Y 

PROVIDER: S-EPMC9668669 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature