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The role of image-guided radiotherapy in prostate cancer: A systematic review and meta-analysis.


ABSTRACT:

Background

Image-guided radiotherapy (IGRT) has gradually been widely promoted in clinical procedure. However, there has been no consensus on the effects of IGRT on toxicity and survival, and no clear level 1 evidence has even been promulgated.

Methods

Medline, EMBASE, PubMed, Cochrane databases and ClinicalTrials.gov were searched for studies comparing IGRT vs non-IGRT or higher frequency IGRT vs lower frequency IGRT during prostate radiotherapy, indexed from database inception to April 2022.

Results

The review included 18 studies (3 randomized clinical trial and 15 cohort studies) involving 6521 men, with a median duration of patient follow-up of 46.2 months in the IGRT group vs 52.7 months in the control group. The meta-analysis demonstrated that IGRT signif

SUBMITTER: Wang S 

PROVIDER: S-EPMC9668680 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature