Metabolic tumor volume predicts long-term survival after transplantation for unresectable colorectal liver metastases: 15 years of experience from the SECA study.

ABSTRACT:

Objective

To report 15 years of experience with metabolic tumor volume (MTV) of liver metastases from the preoperative ¹⁸F-FDG PET/CT to predict long-term survival after liver transplantation (LT) for unresectable colorectal liver metastases (CRLM).

Methods

The preoperative ¹⁸F-FDG PET/CT from all SECA 1 and 2 patients was evaluated. MTV was obtained from all liver metastases. The patients were divided into one group with low MTV (< 70 cm³) and one group with high MTV (> 70 cm³) based on a receiver operating characteristic analysis. Overall survival (OS), disease-free survival (DFS) and post recurrence survival (PRS) for patients with low versus high MTV were compared using the Kaplan-Meier method and log rank test. Clinopathologic

SUBMITTER: Grut H 

PROVIDER: S-EPMC9668778 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature