Added value of quantitative, multiparametric 18F-FDG PET/MRI in the locoregional staging of rectal cancer.

ABSTRACT:

Purpose

The purpose of this study was to determine whether multiparametric positron emission tomography/magnetic resonance imaging (mpPET/MRI) can improve locoregional staging of rectal cancer (RC) and to assess its prognostic value after resection.

Methods

In this retrospective study, 46 patients with primary RC, who underwent multiparametric 18F-fluorodeoxyglucose (FDG) PET/MRI, followed by surgical resection without chemoradiotherapy, were included. Two readers reviewed T- and N- stage, mesorectal involvement, sphincter infiltration, tumor length, and distance from anal verge. In addition, diffusion-weighted imaging (DWI) and PET parameters were extracted from the multiparametric protocol and were compared to radiological staging as well as to the histopathological refere

SUBMITTER: Herold A 

PROVIDER: S-EPMC9668962 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature