Dissociable neural mechanisms of cognition and well-being in youth versus healthy aging.

ABSTRACT: Mental health, cognition, and their underlying neural processes in healthy aging are rarely studied simultaneously. Here, in a sample of healthy younger (n = 62) and older (n = 54) adults, we compared subjective mental health as well as objective global cognition across several core cognitive domains with simultaneous electroencephalography (EEG). We found significantly greater symptoms of anxiety, depression, and loneliness in youth and in contrast, greater mental well-being in older adults. Yet, global performance across core cognitive domains was significantly worse in older adults. EEG-based source imaging of global cognitive task-evoked processing showed reduced suppression of activity in the anterior medial prefrontal default mode network (DMN) region in older adults re

SUBMITTER: Grennan G 

PROVIDER: S-EPMC9669243 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature