Geographic patterns and determinants of antibiotic resistomes in coastal sediments across complex ecological gradients.

ABSTRACT: Coastal areas are highly influenced by terrestrial runoffs and anthropogenic disturbances, commonly leading to ecological gradients from bay, nearshore, to offshore areas. Although the occurrence and distribution of sediment antibiotic resistome are explored in various coastal environments, little information is available regarding geographic patterns and determinants of coastal sediment antibiotic resistomes across ecological gradients at the regional scale. Here, using high-throughput quantitative PCR, we investigated the geographic patterns of 285 antibiotic resistance genes (ARGs) in coastal sediments across a  ~  200  km scale in the East China Sea. Sediment bacterial communities and physicochemical properties were characterized to identify the determinants of sediments antibiotic res

SUBMITTER: Xiong S 

PROVIDER: S-EPMC9669582 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature