Inside-the-body light delivery system using endovascular therapy-based light illumination technology.

ABSTRACT:

Background

Light-based therapies are promising for treating diseases including cancer, hereditary conditions, and protein-related disorders. However, systems, methods, and devices that deliver light deep inside the body are limited. This study aimed to develop an endovascular therapy-based light illumination technology (ET-BLIT), capable of providing deep light irradiation within the body.

Methods

The ET-BLIT system consists of a catheter with a single lumen as a guidewire and diffuser, with a transparent section at the distal end for thermocouple head attachment. The optical light diffuser alters the emission direction laterally, according to the optical fibre's nose-shape angle. If necessary, after delivering the catheter to the target position in the vessel, the diffuser

SUBMITTER: Tsukamoto T 

PROVIDER: S-EPMC9669774 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature