Improving the Sensitivity of Fourier Transform Mass Spectrometer (Orbitrap) for Online Measurements of Atmospheric Vapors.

ABSTRACT: Orbitrap Fourier transform mass spectrometry coupled with chemical ionization (CI) is a new-generation technique for online analysis in atmospheric chemistry. The advantage of the high resolving power of the CI-Orbitrap has been compromised by its relatively low sensitivity to trace compounds (e.g., <10⁶ molecules cm^-3) in complex gaseous mixtures, limiting its application in online atmospheric measurements. In this study, we improve the sensitivity of a Q Exactive Orbitrap by optimizing the parameters governing the signal-to-noise ratio. The influence of other parameters related to ion transmission and fragmentation is also discussed. Using gaseous compounds in an environmental chamber, we show that by increasing the number of ions in the analyzer, the number of micr

SUBMITTER: Cai R 

PROVIDER: S-EPMC9670027 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature