Association between angiotensin-converting enzyme inhibitors and the risk of lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

The association between the use of angiotensin-converting enzyme inhibitors (ACEIs) and lung cancer risk remains controversial. This study evaluated the association between the use of ACEIs and lung cancer risk.

Methods

Records from five databases were searched from inception to 26 January 2022. Clinical studies involving persons aged ≥18 years with at least one year of follow-up and reporting adverse events, including lung cancer, were recorded with separate outcome reports supplied for the ACEIs and control groups. Data were extracted independently by three authors and pooled using a random-effects model. The primary outcome was lung cancer development. Odds ratios (ORs) with 95% confidence intervals (CIs) and lung cancer-related morbidity were calculated.

Re

SUBMITTER: Wu Z 

PROVIDER: S-EPMC9670057 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature