Advances in Drug Discovery and Development in Geriatric Psychiatry.

ABSTRACT:

Purpose of review

This article reviews recent advances in drug discovery and development for geriatric psychiatry. Drug discovery for disorders of the central nervous system is a long and challenging process, with a high attrition rate from the preclinical stages through to marketing a compound. Developing drugs for geriatric neuropsychiatric conditions presents additional challenges, due to the complexity of the symptoms, comorbid diagnoses, and the variability of the population. Despite there being limited success over the past two decades, a number of new approaches have identified potential targets for preclinical development and ultimately clinical testing.

Recent findings

Recent approaches have tried to address specific mechanisms that relate to the disease progression

SUBMITTER: C Conley A 

PROVIDER: S-EPMC9670158 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature